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Article

Transcriptional regulation of the human MIP-1alpha promoter by RUNX1 and MOZ.

Nucleic acids research - 1 Jun 2003

Bristow Claire A P, Shore Paul

Abstract excerpt

The transcription factor RUNX1 (AML-1, PEBP2alphaB and CBFA2) is essential for definitive haematopoiesis, and chromosomal translocations involving the RUNX1 gene are frequently found in acute leukaemias. The gene encoding the histone acetyltransferase MOZ is also rearranged in some acute leukaemias, resulting in the expression of MOZ fusion proteins. MOZ has recently been shown to interact directly with RUNX1,...

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Source

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Identifiers

PMID: 12771199
DOI: 10.1093/nar/gkg401
PMCID: PMC156734

Genes

MIP
RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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