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Article

Likelihood ratio tests for detecting positive selection and application to primate lysozyme evolution.

Molecular biology and evolution - 1 May 1998

Yang Z

Abstract excerpt

An excess of nonsynonymous substitutions over synonymous ones is an important indicator of positive selection at the molecular level. A lineage that underwent Darwinian selection may have a nonsynonymous/synonymous rate ratio (dN/dS) that is different from those of other lineages or greater than one. In this paper, several codon-based likelihood models that allow for variable dN/dS ratios among lineages were...

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Identifiers

PMID: 9580986
DOI: 10.1093/oxfordjournals.molbev.a025957

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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