Article
Detecting past positive selection through ongoing negative selection.
Genome biology and evolution - 1 Jan 2011
Bazykin Georgii A, Kondrashov Alexey S
Abstract excerpt
Detecting positive selection is a challenging task. We propose a method for detecting past positive selection through ongoing negative selection, based on comparison of the parameters of intraspecies polymorphism at functionally important and selectively neutral sites where a nucleotide substitut...
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