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Article

Genetic evidence for transcriptional activation by the yeast IME1 gene product.

Genetics - 1 Apr 1993

Smith H E, Driscoll S E, Sia R A, Yuan H E, Mitchell A P

Abstract excerpt

IME1 is required in yeast for meiosis and for expression of IME2 and other early meiotic genes. IME1 is a 360-amino acid polypeptide with central and C-terminal tyrosine-rich regions. We report here that a fusion protein composed of the lexA DNA-binding domain and IME1 activates transcription in...

Topics

Bacterial Proteins
Fungal Proteins
Gene Expression Regulation, Fungal
Mutation
Nuclear Proteins
Recombinant Fusion Proteins
Repressor Proteins
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Serine Endopeptidases
Structure-Activity Relationship

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transcription Factors

Transcription, Genetic

Transcriptional Activation

Source

Open in PubMed Open full text

Identifiers

PMID: 8462841
DOI: 10.1093/genetics/133.4.775
PMCID: PMC1205399

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8462841-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Genetic evidence for transcriptional activation by the yeast IME1 gene product.PMID 8462841Read ↗

Molecular characterization of the yeast meiotic regulatory gene RIM1.Semantic proximity Read ↗

Induction of meiosis in Saccharomyces cerevisiae depends on conversion of the transcriptional represssor Ume6 to a positive regulator by its regulated association with the transcriptional activator Ime1.Semantic proximity Read ↗

Identification of functionally related genes that stimulate early meiotic gene expression in yeast.Semantic proximity Read ↗

Positive control of yeast meiotic genes by the negative regulator UME6.Semantic proximity Read ↗

Catalytic roles of yeast GSK3beta/shaggy homolog Rim11p in meiotic activation.Semantic proximity Read ↗

YHP1 encodes a new homeoprotein that binds to the IME1 promoter in Saccharomyces cerevisiae.Semantic proximity Read ↗

Identification of the Sin3-binding site in Ume6 defines a two-step process for conversion of Ume6 from a transcriptional repressor to an activator in yeast.Semantic proximity Read ↗

Requirement for RGR1 and SIN4 in RME1-dependent repression in Saccharomyces cerevisiae.Semantic proximity Read ↗

Inactivation of YME1, a member of the ftsH-SEC18-PAS1-CDC48 family of putative ATPase-encoding genes, causes increased escape of DNA from mitochondria in Saccharomyces cerevisiae.Semantic proximity Read ↗

Interaction of Mre11 and Rad50: two proteins required for DNA repair and meiosis-specific double-strand break formation in Saccharomyces cerevisiae.Semantic proximity Read ↗

MEI4, a meiosis-specific yeast gene required for chromosome synapsis.Semantic proximity Read ↗

Role of IME1 expression in regulation of meiosis in Saccharomyces cerevisiae.Semantic proximity Read ↗

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