Article
Genetic evidence for transcriptional activation by the yeast IME1 gene product.
Genetics - 1 Apr 1993
Smith H E, Driscoll S E, Sia R A, Yuan H E, Mitchell A P
Abstract excerpt
IME1 is required in yeast for meiosis and for expression of IME2 and other early meiotic genes. IME1 is a 360-amino acid polypeptide with central and C-terminal tyrosine-rich regions. We report here that a fusion protein composed of the lexA DNA-binding domain and IME1 activates transcription in vivo of a reporter gene containing upstream lexA binding sites. Activation by the fusion protein shares several...
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