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Article

Non-random allelic losses at 3p, 11p and 13q during HPV-mediated immortalization and concomitant loss of terminal differentiation of human keratinocytes.

International journal of cancer - 4 May 1998

Steenbergen R D, Hermsen M A, Walboomers J M, Meijer G A, Baak J P, Meijer C J, Snijders P J

Abstract excerpt

To obtain a comprehensive overview of chromosomal alterations that may underlie human papillomavirus (HPV)-mediated immortalization, 4 foreskin keratinocyte cell lines generated by transfection with either HPV 16 (cell lines FK16A and FK16B) or HPV 18 (FK18A and FK18B) were subjected to chromosomal analysis using comparative genomic hybridization (CGH). Three cell lines were analyzed both in the mortal state...

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Source

Identifiers

PMID: 9579580
DOI: 10.1002/(sici)1097-0215(19980504)76:3<412::aid-ijc20>3.0.co;2-b

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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