Familial adenomatous polyposis.

doi:10.1002/(sici)1098-2388(200006)18:4<314::aid-ssu6>3.0.co;2-9

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Article

Familial adenomatous polyposis.

Seminars in surgical oncology - 1 Jun 2000

Lal G, Gallinger S

Abstract excerpt

Familial adenomatous polyposis (FAP) is a dominantly inherited familial cancer syndrome characterized by an increased predisposition to colorectal cancer and other benign and malignant extra-colonic lesions. FAP has been linked to germline mutations of the adenomatous polyposis coli (APC) gene that encodes a protein with 2,843 amino acids that has important functions in the regulation of cell growth. A...

Topics

Adenomatous Polyposis Coli
Diagnosis, Differential
Genes, APC
Genetic Testing
Genotype
Humans
Pedigree
Phenotype
Polyps

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Identifiers

PMID: 10805953
DOI: 10.1002/(sici)1098-2388(200006)18:4<314::aid-ssu6>3.0.co;2-9

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