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Article

Familial adenomatous polyposis.

Seminars in surgical oncology - 1 Jun 2000

Lal G, Gallinger S

Abstract excerpt

Familial adenomatous polyposis (FAP) is a dominantly inherited familial cancer syndrome characterized by an increased predisposition to colorectal cancer and other benign and malignant extra-colonic lesions. FAP has been linked to germline mutations of the adenomatous polyposis coli (APC) gene that encodes a protein with 2,843 amino acids that has important functions in the regulation of cell growth. A...

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Source

Identifiers

PMID: 10805953
DOI: 10.1002/(sici)1098-2388(200006)18:4<314::aid-ssu6>3.0.co;2-9

Genes

APC
FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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