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Article

SWIM analysis allows rapid identification of residues involved in invasin-mediated bacterial uptake.

Gene - 28 Apr 1998

Krukonis E S, Isberg R R

Abstract excerpt

The Yersinia pseudotuberculosis invasin protein promotes bacterial uptake into normally non-phagocytic cells. Combinations of six alanine substitutions in a region of invasin previously shown to be important for bacterial internalization were analyzed using binomial and codon mutagenesis strategies. A single pool of mutants, potentially containing 64 derivatives with various combinations of alanine substitutions,...

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Identifiers

PMID: 9573344
DOI: 10.1016/s0378-1119(98)00087-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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