Article
Molecular characterization and rescue of acatalasemic mutants of Drosophila melanogaster.
Genetics - 1 Jul 1993
Griswold C M, Matthews A L, Bewley K E, Mahaffey J W
Abstract excerpt
The enzyme catalase protects aerobic organisms from oxygen-free radical damage by converting hydrogen peroxide to molecular oxygen and water before it can decompose to form the highly reactive hydroxyl radical. Hydroxyl radicals are the most deleterious of the activated oxygen intermediates found in aerobic organisms. If formed, they can react with biological molecules in their proximity; the ensuing damage has...
Topics
- Acatalasia
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Catalase
- Cloning, Molecular
- DNA
- Drosophila melanogaster
- Female
- Male
- Molecular Sequence Data