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Article

Lack of transforming growth factor-beta type II receptor expression in human retinoblastoma cells.

Journal of cellular physiology - 1 Jun 1998

Horie K, Yamashita H, Mogi A, Takenoshita S, Miyazono K

Abstract excerpt

Retinoblastoma cells are resistant to transforming growth factor-beta (TGF-beta) activity due to the absence of TGF-beta binding. To further elucidate the mechanism of TGF-beta resistance, we studied the expression of the TGF-beta receptors and SMADs by using the Y79 and WERI-Rb-1 retinoblastoma cell lines. Binding of 125I-TGF-beta1 to serine/threonine kinase receptor type II (TbetaR-II) and TbetaR-I was not seen...

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Source

Identifiers

PMID: 9572475
DOI: 10.1002/(SICI)1097-4652(199806)175:3<305::AID-JCP8>3.0.CO;2-S

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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