Article
Analysis and identification of imprinted genes.
Methods (San Diego, Calif.) - 1 Feb 1998
Kelsey G, Reik W
Abstract excerpt
Genomic imprinting in mammals results in the unequal expression of the two parental alleles of specific genes. The existence of imprinting in the mouse emerged from nuclear transplantation studies and from the abnormal phenotypes associated with uniparental inheritance of particular chromosome se...
Topics
- Alleles
- Animals
- Chromatin
- DNA Methylation
- DNA Replication
- Disease Models, Animal
- Embryo, Mammalian
- Gene Expression
- Imprinting, Psychological
- Mice
- Parthenogenesis
- Phenotype
- Polymerase Chain Reaction
- RNA-Directed DNA Polymerase
- Sequence Analysis, DNA
- Stem Cells
- Translocation, Genetic