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Article

Mechanisms of genomic imprinting.

American journal of human genetics - 1 Oct 2000

Pfeifer K

Abstract excerpt

Imprinted genes represent a curious defiance of normal Mendelian genetics. Mammals inherit two complete sets of chromosomes, one from the mother and one from the father, and most autosomal genes will be expressed from both the maternal and the paternal alleles. Imprinted genes, however, are expressed from only one chromosome, in a parent-of-origin-dependent manner. Because silent and active promoters are present...

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Identifiers

PMID: 10986038
DOI: 10.1086/303101
PMCID: PMC1287882

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