Article
The protein kinase N (PKN) gene PRKCL1/Prkcl1 maps to human chromosome 19p12-p13.1 and mouse chromosome 8 with close linkage to the myodystrophy (myd) mutation.
Genomics - 1 Apr 1998
Bartsch J W, Mukai H, Takahashi N, Ronsiek M, Fuchs S, Jockusch H, Ono Y
Abstract excerpt
Protein kinase N (PKN) is a fatty acid- and Rho-activated serine/threonine protein kinase involved in the regulation of cell motility by association with cytoskeletal components such as neurofilament and alpha-actinin. We determined the chromosomal location of the human PKN gene PRKCL1 by fluores...
Topics
- Animals
- Chromosome Mapping
- Chromosomes, Human, Pair 19
- Female
- Genetic Linkage
- Humans
- In Situ Hybridization, Fluorescence
- Male
- Mice
- Mice, Inbred C57BL
- Muscular Dystrophy, Animal
- Mutation
