Article
Fine mapping of the MLK-3 gene within 11q13 and its exclusion as the MEN1 susceptibility gene.
Human genetics - 1 Jun 1997
Lassam N J, Lin Z, Shennan M G, Courseaux A, Teh B T, Gaudray P, Larsson C
Abstract excerpt
MLK-3 kinase is a widely expressed serine/ threonine kinase that bears multiple protein interaction domains and regulates signals mediated by the stress-responsive pathway. Thus, MLK-3 signaling affects numerous cellular processes, raising the possibility that MLK-3 might play a role in oncogenes...
Topics
- Animals
- Chromosome Mapping
- Chromosomes, Human, Pair 11
- Cricetinae
- Cricetulus
- Genetic Predisposition to Disease
- Humans
- Hybrid Cells
- In Situ Hybridization, Fluorescence
- MAP Kinase Kinase Kinases
- Multiple Endocrine Neoplasia Type 1
- Protein Serine-Threonine Kinases
- Mitogen-Activated Protein Kinase Kinase Kinase 11