Rhabdomyosarcoma-associated locus and MYOD1 are syntenic but separate loci on the short arm of human chromosome 11.

doi:10.1073/pnas.87.6.2182

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Article

Rhabdomyosarcoma-associated locus and MYOD1 are syntenic but separate loci on the short arm of human chromosome 11.

Proceedings of the National Academy of Sciences of the United States of America - 1 Mar 1990

Scrable H J, Johnson D K, Rinchik E M, Cavenee W K

Abstract excerpt

The MYOD1 locus is preferentially expressed in skeletal muscle and at higher levels in its related neoplasm, rhabdomyosarcoma. We have combined physical mapping of the human locus with meiotic and physical mapping in the mouse, together with synteny homologies between the two species, to compare the physical relationship between MYOD1 and the genetically ascertained human rhabdomyosarcoma-associated locus. We...

Topics

Alleles
Animals
Blotting, Southern
Cell Line
Chromosome Mapping
Chromosomes, Human, Pair 11
Gene Library
Genotype
Humans
Hybrid Cells
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

MyoD Protein

Nuclear Proteins

Nucleic Acid Hybridization

Phosphoproteins

RNA, Neoplasm

Rats

Rhabdomyosarcoma

Source

Open in PubMed Open full text

Identifiers

PMID: 2315312
DOI: 10.1073/pnas.87.6.2182
PMCID: PMC53650

Genes

MYOD1
IGF2
LDHA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2315312-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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