Article
Integrated radiation hybrid map of human chromosome 2p13: possible involvement of dynactin in neuromuscular diseases.
Genomics - 15 Jul 1997
Korthaus D, Wedemeyer N, Lengeling A, Ronsiek M, Jockusch H, Schmitt-John T
Abstract excerpt
The genes for the human neuromuscular diseases limb-girdle muscular dystrophy type 2B (LGMD2B) and Miyoshi myopathy are located on chromosome 2p13-p14, and two neuromuscular mutations of the mouse have been mapped to regions homologous to human chromosome 2p13 by conserved synteny, wobbler (wr) o...
Topics
- Animals
- Chromosome Mapping
- Chromosomes, Human, Pair 2
- DNA Primers
- Dynactin Complex
- Genetic Linkage
- Genetic Markers
- Humans
- Hybrid Cells
- Mice
- Microtubule-Associated Proteins
- Muscular Dystrophies
- Mutation
- Neuromuscular Diseases
- Polymerase Chain Reaction