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Article

Drosophila betaHeavy-spectrin is essential for development and contributes to specific cell fates in the eye.

Development (Cambridge, England) - 1 Jun 1998

Thomas G H, Zarnescu D C, Juedes A E, Bales M A, Londergan A, Korte C C, Kiehart D P

Abstract excerpt

The spectrin membrane skeleton is a ubiquitous cytoskeletal structure with several cellular roles, including the maintenance of cell integrity, determination of cell shape and as a contributor to cell polarity. We have isolated mutations in the gene encoding &bgr ;Heavy-spectrin in Drosophila, and have named this essential locus karst. karst mutant individuals have a pleiotropic phenotype characterized by...

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PMID: 9570776
DOI: 10.1242/dev.125.11.2125

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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