Article
Cell shape and interaction defects in alpha-spectrin mutants of Drosophila melanogaster.
The Journal of cell biology - 1 Dec 1993
Lee J K, Coyne R S, Dubreuil R R, Goldstein L S, Branton D
Abstract excerpt
We show that the alpha-spectrin gene is essential for larval survival and development by characterizing several alpha-spectrin mutations in Drosophila. P-element minigene rescue and sequence analysis were used to identify the alpha-spectrin gene as the l(3)dre3 complementation group of the Dras-R...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Southern
- Chromosome Mapping
- Cloning, Molecular
- DNA, Complementary
- Digestive System
- Drosophila melanogaster
- Gamma Rays
- Gene Expression
- Genetic Complementation Test
- Immunoblotting
- Larva
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction