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Article

α-Spectrin and integrins act together to regulate actomyosin and columnarization, and to maintain a monolayered follicular epithelium.

Development (Cambridge, England) - 15 Apr 2016

Ng Bing Fu, Selvaraj Gokul Kannan, Santa-Cruz Mateos Carmen, Grosheva Inna, Alvarez-Garcia Ines, Martín-Bermudo María Dolores, Palacios Isabel M

Abstract excerpt

The spectrin cytoskeleton crosslinks actin to the membrane, and although it has been greatly studied in erythrocytes, much is unknown about its function in epithelia. We have studied the role of spectrins during epithelia morphogenesis using the Drosophila follicular epithelium (FE). As previously described, we show that α-Spectrin and β-Spectrin are essential to maintain a monolayered FE, but, contrary to...

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Source

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Identifiers

PMID: 26952981
DOI: 10.1242/dev.130070
PMCID: PMC4852512

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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