Article
Maintaining epithelial integrity: a function for gigantic spectraplakin isoforms in adherens junctions.
The Journal of cell biology - 29 Sept 2003
Röper Katja, Brown Nicholas H
Abstract excerpt
The Short stop (Shot/Kakapo) spectraplakin is a giant cytoskeletal protein, which exists in multiple isoforms with characteristics of both spectrin and plakin superfamilies. Previously characterized Shot isoforms are similar to spectrin and dystrophin, with an actin-binding domain followed by spectrin repeats. We describe a new large exon within the shot locus, which encodes a series of plakin repeats similar to...
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