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Article

KAI1, a putative marker for metastatic potential in human breast cancer

1 Nov 1997

Abstract excerpt

The KAI1 gene maps to chromosome 11p11.2, is a metastasis-suppressor gene for human prostate cancer and also is involved in the progression of human pancreatic and non-small cell lung cancer. Recently, we showed that introduction of a single copy of normal, neomycin-tagged human chromosome 11 into highly metastatic MDA-MB-435 breast cancer cells suppressed breast cancer metastasis. Concomitantly, KAI1 levels were...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 9570365
DOI: 10.1016/s0304-3835(97)00273-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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KAI1, a putative marker for metastatic potential in human breast cancerPMID 9570365Read ↗

<i>KAI1</i> , a Metastasis Suppressor Gene for Prostate Cancer on Human Chromosome 11p11.2Semantic proximity Read ↗

The expression of the KAI1 gene, a tumor metastasis suppressor, is directly activated by p53Semantic proximity Read ↗

Down-regulation of the KAI1 metastasis suppressor gene during the progression of human prostatic cancer infrequently involves gene mutation or allelic loss.Semantic proximity Read ↗

Investigations of a Possible Role of SNPs in KAI1 Gene on Its Down-Regulation in Breast Cancer.Semantic proximity Read ↗

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Identification of regulatory regions within the KAI1 promoter: a role for binding of AP1, AP2 and p53.Semantic proximity Read ↗

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