Article
Investigations of a Possible Role of SNPs in KAI1 Gene on Its Down-Regulation in Breast Cancer.
Asian Pacific journal of cancer prevention : APJCP - 1 Sept 2020
Kussaibi Haitham, Alkharsah Khaled R
Abstract excerpt
OBJECTIVE: KAI1 (CD82) is a metastasis suppressor gene known to be down-regulated in carcinomas of breast, prostate and many other organs. The mechanism of KAI1 down-regulation is complex and not well understood. Here, we investigate the role of 8 SNPs (not previously studied) in KAI1 gene that could influence its expression in tumor tissue samples of breast cancer patients from the Eastern province of Saudi...
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