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Article

KAI-1/CD82, the molecule and clinical implication in cancer and cancer metastasis.

1 Apr 2009

Abstract excerpt

CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. In recent years apart from its significant involvement in the suppression of...

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PMID: 19224455
DOI: 10.14670/hh-24.519

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