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Article

High prevalence of decreased expression of KAI1 metastasis suppressor in human oral carcinogenesis.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2002

Uzawa Katsuhiro, Ono Kanae, Suzuki Hiroyoshi, Tanaka Chihaya, Yakushiji Takashi, Yamamoto Nobuharu, Yokoe Hidetaka, Tanzawa Hideki

Abstract excerpt

PURPOSE: KAI1 was originally identified in prostate cancer as a metastasis suppressor gene. Recent studies have shown a frequent down-regulation of KAI1 expression in many tumor types, whereas mutation or hypermethylation of the gene is infrequent. The aim of the present study was to examine whether loss of KAI1 expression that might be caused by genetic or epigenetic alterations could contribute to oral...

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PMID: 11895916

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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