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Article

Searching for novel ATF4 target genes in human hepatoma cells by microarray analysis.

Bioscience, biotechnology, and biochemistry - 1 Jun 2016

Maruyama Ryuto, Shimizu Makoto, Ishijima Tomoko, Nakai Yuji, Inoue Jun, Sato Ryuichiro

Abstract excerpt

Activating transcription factor 4 (ATF4) is a transcription factor with an important biological activity. ATF4 is induced by various stresses, such as endoplasmic reticulum stress, through the phosphorylation of eukaryotic translation initiation factor 2α. ATF4 is also involved in lipid metabolism. In the present study, we performed a microarray experiment to identify new ATF4 target genes, particularly those...

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Source

Identifiers

PMID: 26967115
DOI: 10.1080/09168451.2016.1146072

Genes

ATF4
CALCB
CSTA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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