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Article

Decreased membrane permeability in a polymyxin B-resistant Escherichia coli mutant exhibiting multiple resistance to beta-lactams as well as aminoglycosides.

FEMS microbiology letters - 15 Apr 1998

Rahaman S O, Mukherjee J, Chakrabarti A, Pal S

Abstract excerpt

A laboratory mutant of Escherichia coli stably resistant to more than 36,000 U ml-1 of polymyxin B was isolated. The mutant exhibited moderate increases in minimum inhibitory concentration to fluoroquinolones and bacitracin but high levels of cross-resistance to beta-lactams and aminoglycosides. However, it remained susceptible to tetracycline, nalidixic acid and novobiocin. Changes were observed in the outer...

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Identifiers

PMID: 9570116
DOI: 10.1111/j.1574-6968.1998.tb12955.x

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