Article
Outer membrane permeability and beta-lactamase content in Pseudomonas maltophilia clinical isolates and laboratory mutants.
Reviews of infectious diseases - 1 Jan 2000
Mett H, Rosta S, Schacher B, Frei R
Abstract excerpt
Low outer-membrane permeability appears to be responsible for the generally high degree of antibiotic resistance of Pseudomonas maltophilia. Constitutive overproduction of beta-lactamases affects the sensitivity of these bacteria only to those beta-lactam antibiotics that are hydrolyzed by strain...
Topics
- Anti-Bacterial Agents
- Cell Membrane Permeability
- Drug Resistance, Microbial
- Enzyme Induction
- Hydrolysis
- Mutation
- Pseudomonas
- beta-Lactamases
- beta-Lactams
