Article
A single amino acid substitution in PmrB is associated with polymyxin B resistance in clinical isolate of<i>Pseudomonas aeruginosa</i>
10 Jul 2009
Abstract excerpt
Pseudomonas aeruginosa is a major causative agent of hospital-acquired infections and infections in cystic fibrosis patients. Treatment of P. aeruginosa is complicated by the presence of intrinsic and acquired multidrug-resistant isolates. Polymyxin B has often been used as the last option to treat the multidrug-resistant isolates. However, polymyxin B-resistant clinical isolates have been increasingly reported...
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