Article
Characterization of high-level quinolone resistance in Campylobacter jejuni.
Antimicrobial agents and chemotherapy - 1 May 1991
Gootz T D, Martin B A
Abstract excerpt
High-level resistance to quinolones has previously been shown to occur in Campylobacter spp. both in vitro and in patients treated with quinolones. We have selected isolates that are resistant to quinolones by plating cells from a susceptible C. jejuni strain, UA535, on medium containing nalidixic acid at 32 micrograms/ml. Fluctuation analysis indicated that resistance occurred by mutation at a frequency of 5 x...
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