Article
HLA-DRB1 alleles associated with rheumatoid arthritis in Northern Italy: correlation with disease severity.
British journal of rheumatology - 1 Feb 1998
Salvarani C, Macchioni P L, Mantovani W, Bragliani M, Collina E, Cremonesi T, Battistel B, Boiardi L
Abstract excerpt
The aim of the study was to evaluate the relationship between the presence of the 'rheumatoid epitope', defined by a sequence motif in the HLA-DRB1 alleles, rheumatoid factor and disease severity in Northern Italian patients with rheumatoid arthritis (RA). Twenty-nine DR4-positive and 57 DR4-negative RA patients were studied. Each DR4-positive patient was matched with two DR4-negative controls of similar disease...
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