Article
HLA-DRB1*04 subtypes are associated with increased inflammatory activity in early rheumatoid arthritis.
British journal of rheumatology - 1 Sept 1997
Seidl C, Koch U, Buhleier T, Frank R, Möller B, Markert E, Koller-Wagner G, Seifried E, Kaltwasser J P
Abstract excerpt
The sequence polymorphism of HLA-DRB1 molecules in 84 rheumatoid arthritis (RA) patients with early RA has been analysed to evaluate whether particular HLA-DR alleles influence disease progression in the early stage of the disease. Clinical data were analysed by grouping the patients according to disease-associated haplotype combinations (DRB1*04,04/DRB1*04,01/DRB1*04,X/DRB1*01,X) in comparison to patients who...
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