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Article

Modulation of hormone-dependent glucocorticoid receptor function using a tetracycline-regulated expression system.

The Journal of steroid biochemistry and molecular biology - 1 Jan 1998

Wei P, Ahn Y I, Housley P R, Alam J, Vedeckis W V

Abstract excerpt

The glucocorticoid receptor (GR) is a ligand-dependent transcription factor capable of stimulating and inhibiting the expression of target genes. To better understand the biological action of glucocorticoids and the function of GR, we have utilized the tetracycline (Tc)-regulated mammalian expression system to develop a novel cell line, E8.2/GR3, derived from GR null mouse L929 fibroblasts, that exhibits...

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PMID: 9569005
DOI: 10.1016/s0022-1759(97)89907-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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