Article
Glycoprotein C-deficient mutants of two strains of herpes simplex virus type 1 exhibit unaltered adsorption characteristics on polarized or non-polarized cells.
The Journal of general virology - 1 Apr 1998
Griffiths A, Renfrey S, Minson T
Abstract excerpt
Mutants of herpes simplex virus type 1 (HSV-1) strain SC16, lacking each of the dispensable glycoproteins C, G, E, I or J, were examined for their ability to infect the apical or basolateral surfaces of polarized human epithelial cells. None of the mutants was significantly different from the wild-type parent when assayed on either surface. Since a previous report had demonstrated that glycoprotein C (gC) was...
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