Article
Construction and properties of a mutant of herpes simplex virus type 1 with glycoprotein H coding sequences deleted.
Journal of virology - 1 Jan 1992
Forrester A, Farrell H, Wilkinson G, Kaye J, Davis-Poynter N, Minson T
Abstract excerpt
A mutant of herpes simplex virus type 1 (HSV-1) in which glycoprotein H (gH) coding sequences were deleted and replaced by the Escherichia coli lacZ gene under the control of the human cytomegalovirus IE-1 gene promoter was constructed. The mutant was propagated in Vero cells which contained multiple copies of the HSV-1 gH gene under the control of the HSV-1 gD promoter and which therefore provide gH in trans...
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