Construction and properties of a mutant of herpes simplex virus type 1 with glycoprotein H coding sequences deleted.

doi:10.1128/JVI.66.1.341-348.1992

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Article

Construction and properties of a mutant of herpes simplex virus type 1 with glycoprotein H coding sequences deleted.

Journal of virology - 1 Jan 1992

Forrester A, Farrell H, Wilkinson G, Kaye J, Davis-Poynter N, Minson T

Abstract excerpt

A mutant of herpes simplex virus type 1 (HSV-1) in which glycoprotein H (gH) coding sequences were deleted and replaced by the Escherichia coli lacZ gene under the control of the human cytomegalovirus IE-1 gene promoter was constructed. The mutant was propagated in Vero cells which contained mult...

Topics

Animals
Chromosome Deletion
Electrophoresis, Polyacrylamide Gel
Exons
Mutagenesis
Mutation
Simplexvirus
Transfection
Vero Cells
Viral Envelope Proteins
Virion

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