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Article

The SWI/SNF Chromatin-remodeling Complex Is a Cofactor for Tat Transactivation of the HIV Promoter

11 May 2006

Abstract excerpt

Tat is a critical viral transactivator essential for human immunodeficiency virus (HIV) gene expression. Activation involves binding to an RNA stem-loop structure and recruitment of the positive transcription elongation factor b. Tat also induces the remodeling of a single nucleosome in the HIV promoter. However, the mechanism of this remodeling has remained unclear. Knockdown of INI-1 and BRG-1, two components...

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PMID: 16687403
DOI: 10.1074/jbc.m603336200

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The SWI/SNF Chromatin-remodeling Complex Is a Cofactor for Tat Transactivation of the HIV PromoterPMID 16687403Read ↗

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Transcriptional Activation of the Integrated Chromatin-Associated Human Immunodeficiency Virus Type 1 PromoterSemantic proximity Read ↗

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