Epidermal growth factor receptor in mice and men--any applications to clinical practice?

doi:10.3109/07853899709007477

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Article

Epidermal growth factor receptor in mice and men--any applications to clinical practice?

Annals of medicine - 1 Dec 1997

Miettinen P J

Abstract excerpt

The epidermal growth factor receptor (EGF-R) is perhaps the best studied member of tyrosine kinase receptors. Its inactivation by homologous recombination results in three different phenotypes ranging from peri-implantation lethality to postnatal lethality. The mildest form of EGF-R inactivation...

Topics

Animals
Breast
Bronchopulmonary Dysplasia
Enterocolitis, Pseudomembranous
Epithelium
ErbB Receptors
Female
Humans
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases
Intestines
Kidney
Lung
Male
Mammary Glands, Animal
Mice
Morphogenesis

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