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Article

Impaired lung branching morphogenesis in the absence of functional EGF receptor.

Developmental biology - 15 Jun 1997

Miettinen P J, Warburton D, Bu D, Zhao J S, Berger J E, Minoo P, Koivisto T, Allen L, Dobbs L, Werb Z, Derynck R

Abstract excerpt

The mammalian lung develops through branching morphogenesis which is controlled by growth factors, hormones, and extracellular matrix proteins. We have evaluated the role of EGF-receptor signaling in lung morphogenesis by analyzing the developmental phenotype of lungs in mice with an inactivated...

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Source

Identifiers

PMID: 9205141
DOI: 10.1006/dbio.1997.8593

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-9205141-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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