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Article

Genetic deletion of the EGFR ligand epigen does not affect mouse embryonic development and tissue homeostasis.

Experimental cell research - 15 Feb 2013

Dahlhoff Maik, Schäfer Matthias, Wolf Eckhard, Schneider Marlon R

Abstract excerpt

The epidermal growth factor receptor (EGFR) is a tyrosine kinase receptor with manifold functions during development, tissue homeostasis and disease. EGFR activation, the formation of homodimers or heterodimers (with the related ERBB2-4 receptors) and downstream signaling is initiated by the binding of a family of structurally related growth factors, the EGFR ligands. Genetic deletion experiments clarified the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23142483
DOI: 10.1016/j.yexcr.2012.11.001

Genes

EGFR
EGF
ERBB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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