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Article

Regulation of apoptosis by presenilin 1.

Neurobiology of aging - 1 Jan 2000

Wolozin B, Alexander P, Palacino J

Abstract excerpt

Familial Alzheimer's disease is transmitted as an autosomal dominant disorder and, in 5-10% of the cases, is caused by mutations in the coding regions of two homologous genes, Presenilin 1 and 2 (PS1 and PS2). Previously, we have shown that PS2, a homolog of PS1. regulates apoptosis induced in ne...

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Identifiers

PMID: 9562463
DOI: 10.1016/s0197-4580(98)00041-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9562463-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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