Article
Pore formation domain of human pro-apoptotic Bax induces mammalian apoptosis as well as bacterial death without antagonizing anti-apoptotic factors.
Biochemical and biophysical research communications - 13 Feb 1998
Ishibashi Y, Nishimaki K, Asoh S, Nanbu-Wakao R, Yamada T, Ohta S
Abstract excerpt
A trace amount of the pro-apoptotic factor human Bax was sufficient to kill host Escherichia coli (Asoh, S., Nishimaki, K., Nanbu-Wakao, R., and Ohta, S., submitted). The region of Bax lethal to E. coli cells was determined by introducing truncated human bax mutant genes. A peptide corresponding...
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