Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Systemic over-secretion of growth hormone in transgenic mice results in a specific pattern of skeletal modeling and adaptation.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Apr 1998

Tseng K F, Goldstein S A

Abstract excerpt

The effects of growth hormone (GH) over-secretion on bone modeling and remodeling in transgenic mice were investigated using systematic and hierarchical methods. The results showed that continual systemic stimulation of GH over-secretion in mice resulted in an initial increase in bone mass, but its bone quality was not comparable with that of the littermate controls. Further continual over-stimulation of GH...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptation, Physiological
Share to Bone Density

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Bone Development

Share to Genotype

Share to Growth Hormone

Share to Mice, Transgenic

Source

Identifiers

PMID: 9556071
DOI: 10.1359/jbmr.1998.13.4.706

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Systemic over-secretion of growth hormone in transgenic mice results in a specific pattern of skeletal modeling and adaptation.PMID 9556071Read ↗

Mouse cellular cementum is highly dependent on growth hormone status.Semantic proximity Read ↗

Skeletal phenotype of growing transgenic mice that express a function-perturbing form of beta1 integrin in osteoblasts.Semantic proximity Read ↗

Transgenic Mice Reveal Novel Activities of Growth Hormone in Wound Repair, Angiogenesis, and Myofibroblast DifferentiationSemantic proximity Read ↗

Noninvasive Loading of the Murine Tibia: An In Vivo Model for the Study of MechanotransductionSemantic proximity Read ↗

Skeletal response of male mice to anabolic hormone therapy in the absence of the Igfals gene.Semantic proximity Read ↗

Genetic predisposition to low bone mass is paralleled by an enhanced sensitivity to signals anabolic to the skeleton.Semantic proximity Read ↗

Bone response to intermittent parathyroid hormone (PTH) is both genetic and sex specificSemantic proximity Read ↗

Growth hormone injections improve bone quality in a mouse model of osteogenesis imperfecta.Semantic proximity Read ↗

Analysis of Physiological Responses to Thyroid Hormones and Their Receptors in Bone.Semantic proximity Read ↗

Components of growth in mice hemizygous for a MT/bGH transgene.Semantic proximity Read ↗

Bone remodeling: A tissue-level process emerging from cell-level molecular algorithmsSemantic proximity Read ↗

Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.