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Article

Synergistic effect between IL-10 and bcl-2 genotypes in determining susceptibility to systemic lupus erythematosus.

Arthritis and rheumatism - 1 Apr 1998

Mehrian R, Quismorio F P, Strassmann G, Stimmler M M, Horwitz D A, Kitridou R C, Gauderman W J, Morrison J, Brautbar C, Jacob C O

Abstract excerpt

OBJECTIVE: To determine whether genes participating in programmed cell death, including bcl-2, IL-10, Fas-L, and CTLA-4, may contribute to the genetic predisposition to systemic lupus erythematosus (SLE). METHODS: First, intragenic markers for the bcl-2, IL-10, Fas-L, and CTLA-4 genes were characterized and their extent of polymorphism in normal populations was determined. The allelic distribution of these gene...

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Identifiers

PMID: 9550468
DOI: 10.1002/1529-0131(199804)41:4<596::AID-ART6>3.0.CO;2-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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