Article
[Association between Bcl-2 gene polymorphism with systemic lupus erythematosus].
Zhonghua yi xue za zhi - 25 Apr 2002
Wu Hui, Shen Nan, Gu Yueying, Qian Jie, Feng Xuebing, Wang Yuan, Bao Chunde, Chen Shunle
Abstract excerpt
OBJECTIVE: To study the association between bcl-2 gene polymorphism and systemic lupus erythematosus (SLE) in Chinese and detect the synergism between IL-10 and bcl-2 genotypes in determining susceptibility to SLE. METHODS: The peripheral white blood cells from 232 nuclear families of SLE and 106 ethnically matched normal controls were collected and the DNA extracted. The allelic distribution of one...
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