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Article

Structure-function analysis of the trypanosomatid spliced leader RNA.

Nucleic acids research - 1 May 1998

Goncharov I, Xu Y X, Zimmer Y, Sherman K, Michaeli S

Abstract excerpt

In trypanosomes, all mRNAs possess a spliced leader (SL) at their 5' end. SL is added to pre-mRNA via trans -splicing from a small RNA, the SL RNA. To examine structure-function aspects of the trypanosomatid SL RNA, an in vivo system was developed in the monogenetic trypanosomatid Leptomonas collosoma to analyze the function of chimeric and site-directed SL RNA mutants in trans -splicing. Stable cell lines...

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Identifiers

PMID: 9547281
DOI: 10.1093/nar/26.9.2200
PMCID: PMC147514

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