Article
Generating benchmarks for multiple sequence alignments and phylogenetic reconstructions.
Proceedings. International Conference on Intelligent Systems for Molecular Biology - 1 Jan 1997
Stoye J, Evers D, Meyer F
Abstract excerpt
We present a new probabilistic model of evolution of RNA-, DNA-, or protein-like sequences and a tool rose that implements this model. By insertion, deletion and substitution of characters, a family of sequences is created from a common ancestor. During this artificial evolutionary process, the "...
Topics
- Amino Acid Sequence
- Computer Simulation
- Evaluation Studies as Topic
- Evolution, Molecular
- Models, Genetic
- Models, Statistical
- Molecular Sequence Data
- Mutation
- Phylogeny
- Proteins
- Sequence Alignment