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Article

Interactions of the melanocortin-4 receptor with the peptide agonist NDP-MSH.

Journal of molecular biology - 20 Aug 2010

Chapman Kathryn L, Kinsella Gemma K, Cox Alan, Donnelly Dan, Findlay John B C

Abstract excerpt

Melanocortin-4 receptor (MC4R) has an important regulatory role in energy homeostasis and food intake. Peptide agonists of the MC4R are characterized by the conserved sequence His(6)-Phe(7)-Arg(8)-Trp(9), which is crucial for their interaction with the receptor. This investigation utilized the covalent attachment approach to identify receptor residues in close proximity to the bound ligand...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20600126
DOI: 10.1016/j.jmb.2010.06.028
PMCID: PMC3101337

Genes

NDP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interactions of the melanocortin-4 receptor with the peptide agonist NDP-MSH.PMID 20600126Read ↗

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