Article
The D allele of the angiotensin-converting enzyme insertion/ deletion (I/D) polymorphism is a risk factor for type 2 diabetes in a population-based Japanese sample.
Endocrine journal - 1 Aug 2003
Daimon Makoto, Oizumi Toshihide, Saitoh Tamotsu, Kameda Wataru, Hirata Akihiko, Yamaguchi Hiroshi, Ohnuma Hiroshi, Igarashi Masahiko, Tominaga Makoto, Kato Takeo
Abstract excerpt
The association of the ACE gene I/D polymorphism with type 2 diabetes (DM) was examined in a population-based Japanese sample. A total of 902 individuals (490 females and 412 males, age 58.8 +/- 12.2 yr) from a cohort population (n = 3,706) of the Funagata diabetes study were divided into three groups according to genotype: D/D (n = 104), I/D (n = 436) and I/I (n = 362). Chi-square test and ANOVA were used for...
Topics
- Aged
- Alleles
- Asian People
- DNA Transposable Elements
- Diabetes Mellitus, Type 2
- Female
- Gene Deletion
- Genetic Predisposition to Disease
- Humans
- Logistic Models