Article
Effect of interleukin-6 deficiency on the formation of periapical lesions after pulp exposure in mice.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics - 1 Jul 2001
Huang G T, Do M, Wingard M, Park J S, Chugal N
Abstract excerpt
OBJECTIVE: The multifunctional cytokine interleukin-6 (IL-6) has actions on multiple cell types, including promotion of the development of immune cells and osteoclasts. Periapical inflammation as the result of root canal infection is characterized by the accumulation of inflammatory cells and bone resorption. The effect of IL-6 on periapical lesion formation after pulpal infection is unknown. We sought to...
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