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Article

Genetic and developmental characterization of Dmca1D, a calcium channel alpha1 subunit gene in Drosophila melanogaster.

Genetics - 1 Mar 1998

Eberl D F, Ren D, Feng G, Lorenz L J, Van Vactor D, Hall L M

Abstract excerpt

To begin unraveling the functional significance of calcium channel diversity, we identified mutations in Dmca1D, a Drosophila calcium channel alpha1 subunit cDNA that we recently cloned. These mutations constitute the l(2)35Fa lethal locus, which we rename Dmca1D. A severe allele, Dmca1D(X10), truncates the channel after the IV-S4 transmembrane domain. These mutants die as late embryos because they lack vigorous...

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Identifiers

PMID: 9539432
DOI: 10.1093/genetics/148.3.1159
PMCID: PMC1460043

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