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Article

Drosophila calmodulin mutants with specific defects in the musculature or in the nervous system.

Genetics - 1 Nov 2003

Wang Bo, Sullivan Kathleen M C, Beckingham Kathy

Abstract excerpt

We have studied lethal mutations in the single calmodulin gene (Cam) of Drosophila to gain insight into the in vivo functions of this important calcium sensor. As a result of maternal calmodulin (CaM) in the mature egg, lethality is delayed until the postembryonic stages. Prior to death in the first larval instar, Cam nulls show a striking behavioral abnormality (spontaneous backward movement) whereas a mutation,...

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Identifiers

PMID: 14668380
DOI: 10.1093/genetics/165.3.1255
PMCID: PMC1462851

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Source receipt: pubmed, retrieved 7 Sept 2026.

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