Article
Estrogen receptor polymorphism at codon 325 and risk of breast cancer in women before age forty.
Journal of the National Cancer Institute - 1 Apr 1998
Southey M C, Batten L E, McCredie M R, Giles G G, Dite G, Hopper J L, Venter D J
Abstract excerpt
BACKGROUND: The estrogen receptor (ER) protein is believed to play a role in the development and progression of breast cancer. In a previously published U.S. clinic-based study, a polymorphism in the ER gene (codon 325, CCC --> CCG) was found to be more common in 34 case subjects with a family history of breast cancer than in 154 case subjects without such a history (mean allele frequencies +/- standard error =...
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